A rare but hard-to-treat form of breast cancer is driven by a newly discovered gene, researchers have found.
ZNF703 is the first oncogene to be discovered in five years, and it could lead to more effective treatments down the road, Cancer Research UK said.
Oncogenes tell healthy cells to divide when needed. But in tumours, they are overactive and the cancer multiply unstoppably. The oncogene act like a stuck accelerator that leads a car to speed out of control.
In Friday’s online issue of the journal EMBO Molecular Medicine, scientists from Cancer Research UK’s Cambridge Research Institute and the British Columbia Cancer Agency in Vancouver said evidence strongly suggests ZNF703 is a new oncogene.
To come to that conclusion, they tested gene activity in 1,172 breast tumour samples that were estrogen receptor-positive. (more…)